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Section: Partnerships and Cooperations

International Initiatives

ECOS-CONICYT

B. Perthame and K. Vilches take part in the Franco-Chilean project `Functional analysis, asymptotics and dynamics of fronts' headed by J. Dolbeault (University Paris-Dauphine) funded by ECOS-CONICYT.

EuroMed 3+3

M3CD, Mathematical Models and Methods in Cell Dynamics, a transmediterranean EuroMed3+3 program, has begun in January 2012 for 4 years, under the coordination of J. Clairambault. It associates 2 Inria teams: Bang and Dracula (Mostafa Adimy, Lyon) with the IAC-CNR in Rome (Roberto Natalini), the LMDP team in Marrakech (Hassan Hbid) and the MoMinBi team at Institut Pasteur, Tunis (Slimane BenMiled, Amira Kebir) to work on the general theme “Mathematical Models and Methods in Cell Dynamics”. It has fostered in 2013 visits of students to Paris and Lyon, for Y. Bourfia, PhD student at Marrakech and UPMC, who works under the supervision of H. Hbid, M. Adimy and J. Clairambault and for Rym Jaroudi, M2 student at the University of Tunis, who works under the supervision of Slimane BenMiled and Amira Kebir.

A 2-day M3CD workshop, organised by Hassan Hbid, following a first one organised in November 2012 in Tunis, will take place in January 2014 (27-28) in Marrakech. Newcomers, researchers from the Northern side, who will be present in this workshop, will join the network in 2014: Marcello Delitala (Polito, Turin) and Oscar Angulo (University of Valladolid).

Xuguang Qi-Hubert Curien program

C. Emako-Kazianou and N. Vauchelet take part in a Xuguang Qi-Hubert Curien program funded by CampusFrance in collaboration with Shanghai Jiao Tong university. This program no 30043VM entitled “PDE models for cell self-organization" is headed by N. Vauchelet and allows visits for both parts of the project. The chinese researchers involved in this program are Min Tang and Jie Lao.

Inria International Partners

  1. German Research Ministry (BMBF) funded project on the systems biology of lung cancer. The major aim is to better understand the early metastasis formation and invasion of lung cancer, including therapeutical options. Data on all levels ranging from intracellular up to organ level will be used to establish successively an integrated multiscale model of cellular and migration decisions in lung cancer. A particular focus will be on dissecting how cellular organisation and communication in spheroid cultures and co-cultures of lung cancer cell lines with selected endothelial cells affects information processing and the proliferation and migration decisions downstream. To reveal the inhomogeneous spatio-temporal organisation in these tumour growth models, specific probes for medical imaging, quantify extracellular cytokine concentrations will be used, and the effects of pharmacological inhibitors be monitored. By data and model integration, parameters should be identified that critically determine early spread and facilitate to predict possibilities for improved therapeutic options.

    The project coordinator is Ursula Klingmueller, German Cancer Research Centre (DKFZ), Heidelberg (http://www.lungsys.de/ )

  2. German Research Ministry (BMBF) funded project on the systems biology of liver (Virtual Liver Network). The aim of the VLN project is to set up multiscale models of liver. The Virtual Liver will be a dynamic model that represents, rather than fully replicates, human liver physiology morphology and function, integrating quantitive data from all levels of organisation. Our part ranges from the intracellular up to the level of groups of liver lobules. A liver lobule is the basic repetitive functional unit of liver. Applications are explained in the text. The networks has 69 Principle Investigators organised in about 10 work packages, each of which have a number of sub-projects (http://www.virtual-liver.de/about/ ).